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Comparison between Different Measures of Body Fat with Kidney Function Decline and Incident Chronic Kidney Disease

Friday, May 19, 2017

In this study, a higher amount of body fat was linked with an increased risk of developing chronic kidney disease.

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Determining activity count cut-points for measurement of physical activity using the Actiwatch2 accelerometer

Friday, February 3, 2017

The Actiwatch2 demonstrated the ability to discriminate different intensities of physical activity among adult females.

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Measuring the health-related Sustainable Development Goals in 188 countries: A baseline analysis from the Global Burden of Disease Study 2015

Wednesday, September 28, 2016

Background: In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030.

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Innovative approach for increasing physical activity among breast cancer survivors: Protocol for Project MOVE, a quasi-experimental study

Thursday, September 8, 2016

Introduction: Physical activity is a cost-effective and non-pharmaceutical strategy that can help mitigate the physical and psychological health challenges associated with breast cancer survivorship.

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Men in rural and remote locations: Their preferences for worksite wellness programs

Friday, July 29, 2016

Dale, L et al. (2016). Men in rural and remote locations: Their preferences for worksite wellness programs. Journal of Occupational & Environmental Medicine, 58(7), e279-80.

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Rationale, design, and methods for Canadian Alliance for Healthy Hearts and Minds cohort study (CAHHM) - A Pan Canadian cohort study

Wednesday, July 27, 2016

Background: The Canadian Alliance for Healthy Hearts and Minds (CAHHM) is a pan-Canadian, prospective, multi-ethnic cohort study being conducted in Canada.

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Measurement of circulating phospholipid fatty acids: Association between relative weight percentage and absolute concentrations

Friday, June 17, 2016

Objective: Most epidemiologic studies of circulating phospholipid fatty acids (PLFAs) and disease risk have used the relative concentration (percentage of total) of each fatty acid as the measure of exposure.

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Examining the relationship between personality and affect-related attributes and adolescents' intentions to try smoking using the Substance Use Risk Profile Scale

Monday, February 22, 2016

Assessments of adolescents' smoking intentions indicate that many are susceptible to smoking initiation because they do not have resolute intentions to abstain from trying smoking in the future.

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Small-area spatio-temporal analyses of bladder and kidney cancer risk in Nova Scotia, Canada

Friday, February 19, 2016

Background: Bladder and kidney cancers are the ninth and twelfth most common type of cancer worldwide, respectively. Internationally, rates vary ten-fold, with several countries showing rising incidence.

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The effect of Tai Chi for chronic conditions: A systematic review and meta-analysis

Monday, January 18, 2016

Chen EYW, Hunt MA, Campbell KL, Pelli K, Reid DR. (in press). The effect of Tai Chi for chronic conditions: A systematic review and meta-analysis.  Br J Sports Med (accepted August 13, 2015)

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Physical activity, physical fitness and body composition of Canadian shift workers

Monday, January 18, 2016

Neil-Sztramko SE, Gotay CC, Demers PE, Campbell KL. (in press). Physical activity, physical fitness and body composition of Canadian shift workers: Data from the Canadian Health Measures Survey Cycle 1 and 2. J Occup Environ Med (accepted July 13 2015). 

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Utility of equations to estimate peak oxygen uptake and work rate from a 6-minute walk test in patients with COPD in a clinical setting

Monday, January 18, 2016

Kirkham AA, Pauhl KE, Elliott RM, Scott JA, Doria SC, Davidson HK, Neil-Sztramko SE, Campbell KL, Camp PG. in press).

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Interval versus continuous aerobic exercise training in breast cancer survivors-a pilot RCT

Monday, January 18, 2016
Background: Exercise therapy is being explored in a variety of cancer populations to counteract treatment-related deconditioning.
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A qualitative study exploring how school community environments shape the food choices of adolescents with overweight/obesity

Tuesday, December 1, 2015
This study explored perceived barriers and facilitators to healthful eating in schools and communities among overweight teens who completed an E-health intervention.
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Experiences of overweight/obese adolescents in navigating their home food environment

Tuesday, December 1, 2015
OBJECTIVE:
To explore perceived factors that impede or facilitate healthful eating within the home environment among overweight/obese adolescents.
DESIGN:
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Fatigue and mortality: from description to action

Tuesday, September 22, 2015

Patient-reported outcomes, including quality of life and symptom reports, have contributed to cancer care and research in many ways,1 including improved prognostication of how long patients with cancer will live.

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Health-related physical fitness assessment in a community-based cancer rehabilitation setting

Tuesday, September 1, 2015
Purpose: Assessment of physical fitness is important in order to set goals, appropriately prescribe exercise, and monitor change over time.
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Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition

Friday, August 28, 2015

Background The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and transparent data sources to enable comparisons of health

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Depressive trajectories and risk of disability and mortality in older adults: longitudinal findings from the Health, Aging and Body Composition Study

Monday, August 3, 2015
Background. Depression and disability are closely linked. Less is known regarding clinical and subclinical depressive symptoms over time and risk of disability and mortality.
 
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Top 10 research questions related to physical activity and cancer survivorship

Monday, June 1, 2015
In the United States, there are more than 14 million cancer survivors. Many of these survivors have been treated with multimodal therapy including surgery, radiation therapy, chemotherapy, and targeted therapies.
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The Global Burden of Cancer 2013

Thursday, May 28, 2015
This study, led by the Global Burden of Disease Cancer Collaboration, estimates the cancer burden in individual countries to help guide local cancer control policy and programs.
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Asbestos in Canada: time to change our legacy

Monday, May 4, 2015

Drs. Dummer and Gotay call for Canadian policy-makers to make a time-specific ban on asbestos use in Canada.

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No effects of caloric restriction and exercise on radiation repair capacity

Friday, May 1, 2015
Introduction: Maintenance of normal weight and higher levels of physical activity are associated with a reduced risk of several types of cancer.
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Cancer risk: Prevention is crucial

Friday, February 13, 2015

As cancer prevention scientists, we read C. Tomasetti and B. Vogelstein's Report “Variation in cancer risk among tissues can be explained by the number of stem cell divisions” (2 January, p. 78) with considerable interest.

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The effectiveness of exercise interventions for improving health-related quality of life from diagnosis through active cancer treatment

Thursday, January 15, 2015

In the study, the researchers assessed the effectiveness of exercise interventions for improving health-related quality of life for adults immediately

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CVD prevention in 2014: Advances in the prevention of cardiovascular disease

Wednesday, January 7, 2015

In this article, the authors discuss the major advances in CVD prevention in 2014.

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Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: A systematic analysis for the Global Burden of Disease Study 2013

Friday, December 19, 2014

Up-to-date evidence on levels and trends for age-sex-specific all-cause and cause-specific mortality is essential for the formation of global, regional, and national health policies.

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A single bout of high-intensity aerobic exercise facilitates response to paired associative stimulation and promotes sequence-specific implicit motor learning

Monday, December 1, 2014
The objectives of the present study were to evaluate the impact of a single bout of high-intensity aerobic exercise on 1) long-term potentiation (LTP)-like neuroplasticity via response to paired associative stimulation (PAS) and 2) the temporal and spatial components o
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Aerobic capacity and upper limb strength are reduced in women diagnosed with breast cancer: A systematic review

Monday, December 1, 2014
QUESTION:
What are typical values of physical function for women diagnosed with breast cancer and how do these compare to normative data?
DESIGN:
Systematic review with meta-analysis.
PARTICIPANTS:
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Are exercise programs effective for improving health-related quality of life among cancer survivors? A systematic review and meta-analysis

Thursday, November 13, 2014

This study evaluated the effectiveness of exercise interventions on overall health-related quality of life and its domains among cancer survivors.

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Youth health care utilization in Nova Scotia: what is the role of age, sex and socio-economic status?

Saturday, November 1, 2014
Youth have distinct health care needs that are not always met within a framework designed for children or adults. In Canada, little attention has been given to how youth utilize health care services and limited data are available.
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Effect of web-based messages on girls’ knowledge and risk perceptions related to cigarette smoke and breast cancer: 6-month follow-up of a randomized controlled trial

Monday, October 6, 2014

This study evaluated the efficacy of targeted messages about the increased risk of breast cancer associated with cigarette smoke exposure.

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Exercise training and immune crosstalk in the tumor microenvironment: Exploring the paradigms of exercise-induced immune modulation and exercise-induced myokines

Wednesday, October 1, 2014
Observational research suggests that exercise may reduce the risk of breast cancer and improve survival.
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Premature mortality due to social and material deprivation in Nova Scotia, Canada

Wednesday, October 1, 2014

Inequalities in health attributable to inequalities in society have long been recognized. Typically, those most privileged experience better health, regardless of universal access to health care.

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Predicting adherence of formerly sedentary adults to a 12-month exercise intervention

Monday, September 1, 2014
The purpose of this study was to (a) examine demographic, psychosocial, and physiological predictors of exercise adherence in a yearlong exercise intervention and (b) describe the trajectory of adherence over time.
 
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Arsenic in private drinking water wells: An assessment of jurisdictional regulations and guidelines for risk remediation in North America

Monday, September 1, 2014

Arsenic is a known carcinogen found globally in groundwater supplies due to natural geological occurrence.

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Update on the Colon Health and Life-Long Exercise Change Trial: A Phase III study of the impact of an exercise program on disease-free survival in colon cancer survivors

Monday, September 1, 2014
The Colon Health and Life-Long Exercise Change (CHALLENGE) trial is evaluating the effects of a 3-year exercise program on disease-free survival in 962 patients with resected high-risk stage II or stage III colon cancer.
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Core Symptom Measures in Cancer Clinical Trials

Tuesday, August 26, 2014

Dr. Gotay discusses implications of four recently published articles.

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Health-related interventions among night shift workers: A critical review of the literature

Tuesday, July 1, 2014

This critical review synthesized and evaluated interventions that have been implemented among shift workers to reduce chronic health effects.

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Arsenic in drinking water and urinary tract cancers: A systematic review of 30 years of epidemiological evidence

Monday, June 2, 2014

Arsenic in drinking water is a public health issue affecting hundreds of millions of people worldwide.

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Attention to principles of exercise training: a review of exercise studies for survivors of cancers other than breast

Sunday, June 1, 2014
Randomised controlled trials (RCTs) can evaluate how well a particular exercise programme reduces cancer treatment-related side effects.
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Does change in health-related quality of life score predict survival? Analysis of EORTC 08975 lung cancer trial

Tuesday, May 13, 2014

Little is known about whether changes in health-related quality of life (HRQoL) scores from baseline during treatment also predict survival, which we aim to investigate in this study.

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What is the role of obesity in the aetiology of arsenic-related disease?

Thursday, May 1, 2014

Consumption of arsenic contaminated drinking water causes a large variety of adverse health outcomes.

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Quality of life and disparities among long-term cervical cancer survivors

Saturday, April 5, 2014

Little population-based research has been done on social, economic, and environmental factors affecting quality of life (QOL) among long-term cancer survivors.

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Designing tailored messages about smoking and breast cancer: A focus group study with youth

Saturday, March 1, 2014

The purpose of this study was to design an approach to supporting the development of gender- and Aboriginal-specific messages regarding the link between tobacco exposure and breast cancer, drawing on youth perspectives.

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Physical activity levels of cancer survivors in Canada: findings from the Canadian Community Health Survey

Saturday, March 1, 2014
PURPOSE: Physical activity may reduce many side effects of cancer treatment and may improve survival.
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Lateral trunk lean gait modification increases the energy cost of treadmill walking in those with knee osteoarthritis

Monday, February 3, 2014
OBJECTIVE:
To compare the energy expenditure of increased lateral trunk lean walking - a suggested method of reducing medial compartment knee joint load - compared to normal walking in a population of older adults with medial knee osteoarthritis (OA).
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A global analysis of multitrial data investigating quality of life and symptoms as prognostic factors for survival in different tumor sites

Wednesday, January 15, 2014

The objective of this study was to examine the prognostic value of baseline health-related quality of life (HRQOL) for survival with regard to different cancer sites using 1 standardized and validated patient self-assessment tool.

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Initial impact of tailored web-based messages about cigarette smoke and breast cancer risk on boys' and girls' risk perceptions and information seeking: Randomized controlled trial

Tuesday, December 10, 2013

Recent evidence indicates a causal link between both active smoking and secondhand smoke (SHS) exposure and breast cancer (BC).

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Promoting neuroplasticity for motor rehabilitation after stroke: considering the effects of aerobic exercise and genetic variation on brain-derived neurotrophic factor

Sunday, December 1, 2013
Recovery of motor function after stroke involves relearning motor skills and is mediated by neuroplasticity. Recent research has focused on developing rehabilitation strategies that facilitate such neuroplasticity to maximize functional outcome poststroke.
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Independent and combined effects of dietary weight loss and exercise on leukocyte telomere length in postmenopausal women

Sunday, December 1, 2013
 
OBJECTIVE: Investigate the effects of 12 months of dietary weight loss and/or aerobic exercise on leukocyte telomere length in postmenopausal women.
 
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Physical activity levels of cancer survivors in Canada: Findings from the Canadian Community Health Survey

Wednesday, November 20, 2013

Physical activity may reduce many side effects of cancer treatment and may improve survival.

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Reliability and validity of the Performance Recorder 1 for measuring isometric knee flexor and extensor strength

Friday, November 1, 2013
Muscular strength is a key parameter of rehabilitation programs and a strong predictor of functional capacity.
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Higher capecitabine AUC in elderly patients with advanced colorectal cancer

Tuesday, October 1, 2013

The aging process is accompanied by physiological changes including reduced glomerular filtration and hepatic function, as well as changes in gastric secretions.

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Adherence rates and correlates in long-term hormonal therapy

Sunday, September 1, 2013

Breast cancer outcomes have improved markedly in the past few decades, due in part to the use of adjuvant hormonal therapy.

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Quantifying Canadians’ use of the Internet as a source of information on behavioural risk factor modifications related to cancer prevention

Friday, May 31, 2013

The purpose of this study was to quantify the frequency and timing of Canadians’ Internet searches for information on modifying cancer prevention-related behavioural risk factors.

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Feasibility and value of PatientViewpoint: A web system for patient-reported outcomes assessment in clinical practice

Monday, April 1, 2013

The PatientViewpoint website collects patient-reported outcomes and links them with the electronic health record to aid patient management. This pilot test evaluated PatientViewpoint's use, usefulness, and acceptability to patients and clinicians.

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Updating the Canadian obesity maps: An epidemic in progress

Wednesday, February 27, 2013

Obesity is a growing problem in Canada and worldwide. We created obesity maps that show changing rates over time and geography.

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Effect of completion-time windows in the analysis of health-related quality of life outcomes in cancer patients

Tuesday, January 1, 2013

This study examined if health-related quality of life scores on questionnaires were affected by the time at which the questionnaire was completed.

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Content validity and feasibility of the Care Notebook to assess cancer-related quality of life in Hawaii

Saturday, December 15, 2012

This study used focus groups to examine the content validity and feasibility of the Care Notebook among Hawaii residents.

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Complementary and alternative medicine use and breast cancer prognosis: A pooled analysis of four population-based studies of breast cancer survivors

Saturday, December 1, 2012

Complementary and alternative medicine (CAM) use is common among breast cancer survivors, but little is known about its impact on survival.

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The relationship between complementary and alternative medicine use and breast cancer early detection

Friday, November 30, 2012

This study provides the first systematic review of research on complementary and alternative medicine and breast cancer screening.

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Risk of late mortality and second malignant neoplasms among 5-year survivors of young adult cancer: A report of the Childhood, Adolescent, and Young Adult Cancer Survivors Research Program

Wednesday, September 12, 2012

The long-term risks of mortality and second malignant neoplasm among survivors of young adult cancer were assessed.

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Exercise interventions on health-related quality of life for cancer survivors

Wednesday, August 15, 2012

Cancer survivors experience numerous disease and treatment-related adverse outcomes and poorer health-related quality of life (HRQoL). Exercise interventions are hypothesized to alleviate these adverse outcomes.

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A prospective analysis of the influence of older age on physician and patient decision-making when considering enrollment in breast cancer clinical trials

Wednesday, June 20, 2012

Patients older than 65 years are underrepresented in clinical trials. We conducted a prospective study (SWOG S0316) to determine physician- and patient-perceived barriers to breast cancer clinical trial enrollment for older patients.

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Fear of cancer recurrence: A systematic literature review of self-report measures

Friday, June 1, 2012

Prior research has shown that many cancer survivors experience ongoing fears of cancer recurrence (FCR) and that this chronic uncertainty of health status during and after cancer treatment can be a significant psychological burden.

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Feasibility of a lifestyle intervention on body weight and serum biomarkers in breast cancer survivors with overweight and obesity

Monday, April 2, 2012

Physical inactivity and being overweight or obese are lifestyle factors that put breast cancer survivors at a higher risk for a cancer recurrence and/or development of other chronic diseases.

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A model of cancer prevention in British Columbia: The Breast Cancer Prevention and Risk Assessment Clinic

Sunday, April 1, 2012

Approximately 1 in 9 Canadian women will develop breast cancer at some time in life, while 1 in 29 can be expected to die from the disease.

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Patient self-reports of symptoms and clinician ratings as predictors of overall cancer survival

Wednesday, December 21, 2011

The National Cancer Institute's Common Terminology Criteria for Adverse Events (NCI-CTCAE) reporting system is widely used by clinicians to measure patient symptoms in clinical trials.

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Macronutrients, vitamins, and minerals intake and risk of esophageal squamous cell carcinoma: A case-control study in Iran

Tuesday, December 20, 2011

Although Iran is a high-risk region for esophageal squamous cell carcinoma (ESCC), dietary factors that may contribute to this high incidence have not been thoroughly studied.

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Adherence to long-term adjuvant hormonal therapy for breast cancer

Thursday, December 1, 2011

Tamoxifen is an essential drug in treating hormone receptor-positive breast cancer and has been used successfully for the past three decades. More recently, aromatase inhibitors (AIs) have also shown great promise in reducing breast cancer recurrence.

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Minimal important differences for interpreting health-related quality of life scores from the EORTC QLQ-C30 in lung cancer patients participating in randomized controlled trials

Tuesday, November 1, 2011

This study examined changes in health-related quality of life scores in patients with non-small-cell lung cancer.

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Examining the relationships among health-related quality-of-life indicators in cancer patients participating in clinical trials: A pooled study of baseline EORTC QLQ-C30 data

Saturday, October 1, 2011

Cancer patients experience multiple and concurrent health-related problems and symptoms due to their illness and therapies.

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Minimal clinically meaningful differences for the EORTC QLQ-C30 and EORTC QLQ-BN20 scales in brain cancer patients

Thursday, September 1, 2011

This study examined changes in health-related quality of life scores in patients with brain cancer.

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Patient-reported outcomes: Clinical trials in ovarian cancer

Sunday, May 1, 2011

The use of patient-reported outcomes (PROs) has become an integral part of patient and treatment outcome assessment in the design of contemporary clinical trials in oncology.

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Factors affecting survival among women with breast cancer in Hawaii

Tuesday, February 1, 2011

This study examined the role of several factors in the survival of breast cancer patients representing six ethnic groups in Hawaii.

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Differential item functioning (DIF) analyses of health-related quality of life instruments using logistic regression

Wednesday, August 4, 2010

Differential item functioning (DIF) methods can be used to determine whether different subgroups respond differently to particular items within a health-related quality of life (HRQoL) subscale, after allowing for overall subgroup differences in that scale.

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Interpretation of differential item functioning analyses using external review

Tuesday, June 1, 2010

Differential item functioning (DIF) analyses are used to determine whether certain groups respond differently to a particular item of a test or questionnaire; however, these do not explain the reasons for observed response differences.

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Cancer prevention: Major initiatives and looking into the future

Thursday, April 1, 2010

Cancer is one of the major causes of death in countries across the world. However, at least half of cancers could be prevented.

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Added value of health-related quality of life measurement in cancer clinical trials: The experience of the NCIC CTG

Thursday, April 1, 2010

Health-related quality-of-life (HRQoL) data are often included in Phase III clinical trials.

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Using quality of life measures in a Phase I clinical trial of noni in patients with advanced cancer to select a Phase II dose

Tuesday, December 1, 2009

The purpose of this study was to determine a maximum tolerated dose of noni in cancer patients and whether an optimal quality of life-sustaining dose could be identified as an alternative way to select a dose for subsequent Phase II efficacy trials.

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PatientViewpoint: A website for patient-reported outcomes assessment

Tuesday, September 1, 2009

The purpose of this study was to develop a prototype website to collect patient-reported outcomes in outpatient clinical oncology and link the data with the electronic medical record (EMR).

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Differential item functioning (DIF) in the EORTC QLQ-C30: A comparison of baseline, on-treatment and off-treatment data

Friday, February 27, 2009

Differential item functioning (DIF) analyses can be used to explore translation, cultural, gender or other differences in the performance of quality of life (QoL) instruments. These analyses are commonly performed using "baseline" or pretreatment data.

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Adaptation and quality of life among long-term cervical cancer survivors in the military health care system

Wednesday, October 1, 2008

This study assessed quality of life in long-term cervical cancer survivors eligible for health care in the military health system.

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The relationship between overall quality of life and its subdimensions was influenced by culture: Analysis of an international database

Friday, August 1, 2008

This study investigated whether geographic and cultural factors influenced the relationship between several quality of life scales.

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Survivorship research based in integrated healthcare delivery systems: The Cancer Research Network.

Sunday, June 1, 2008

Integrated healthcare delivery systems present unique opportunities for cancer survivorship research. The National Cancer Institute funds the Cancer Research Network (CRN) to leverage these capabilities for all types of cancer research, including survivorship.

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Prognostic factor analysis of health-related quality of life data in cancer: A statistical methodological evaluation

Tuesday, April 1, 2008

A significant body of research exists in oncology to identify and evaluate prognostic factors, historically focused on histology, clinical stage and laboratory parameters.

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The prognostic significance of patient-reported outcomes in cancer clinical trials

Monday, March 10, 2008

Patient-reported outcomes (PROs), routinely collected as a part of cancer clinical trials, have been linked with survival in numerous clinical studies, but a comprehensive critical review has not been reported.

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Development of a family intervention for Native Hawaiian women with cancer: A pilot study

Tuesday, January 1, 2008

Native Hawaiian women have high cancer rates and low survival rates. As with other women, a major source of support for Native Hawaiian women is their families.

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